Clinical Research

Yale researchers have introduced countless medical and health advances over the last century, including the first success with antibiotics in the United States and the first use of chemotherapy to treat cancer. Yale scientists identified Lyme disease and discovered genes responsible for such disorders as high blood pressure, osteoporosis, dyslexia, and Tourette's syndrome. We did early work on the artificial heart and developed the first insulin pump to treat diabetes. Our investigators are also world-renowned for basic science research, including groundbreaking discoveries about how the cell and its components function at the molecular level.

At the Yale Medicine Department of Therapeutic Radiology, we conduct clinical research in almost all types of cancer including head and neck, breast, lung, Hodgkin's disease, non-Hodgkin's lymphomas, all of the major gastrointestinal cancers, glioblastoma multiforme, and other neurological based malignancies, genito-urinary cancer, and common childhood malignancies including Wilm's tumor, neuroblastoma and leukemia.

Most of our studies involve collaborative efforts with physicians from other specialties, most commonly medical oncology, pediatric oncology and the various surgical sub-specialties. We also offer patients the opportunity to participate in multi-institutional cooperative group trials and other collaborative inter-institutional endeavors.

Our department is the home of the oldest Tumor Registry in the U.S. Founded in 1926, the Registry collects, manages, and analyzes data on patients diagnosed with cancer or related benign diseases. Our focus is advancing the understanding of the mechanisms of cancer and the impact of cancer treatment. Basic research in radiobiology, discovery of the underlying mechanisms of radiation response, and DNA repair are also high priorities for our department.

Clinical trials are vital to advancing research and bringing the newest treatments and technologies to patients as quickly and as safely as possible. If you would like to consider participating in a clinical trial, click here to for a database of available clinical trials or visit to view available clinical trials or learn more about clinical research at Yale.