The eye and its surrounding structures (eyelids, orbit) represent a unique portion of the human anatomy. The eye itself is an incredibly complex structure, composed of specialized “layers” of tissue, each with a specific histology and function. The Ophthalmic Pathology Service evaluates the broad range of specimens received from in and around the eye, including the skin of the eyelid, the conjunctiva, the cornea, the orbit, and the globe (eyeball). This includes both inflammatory andneoplastic lesions.